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Senior Scientist/Principal Scientist, Encoded Peptide Libraries
Senior Scientist/Principal Scientist, Encoded Peptide Libraries-March 2024
Basel
Mar 16, 2025
ABOUT NOVARTIS
At Novartis, we’re reimagining medicine to improve people’s lives through innovative science and technology.
10,000+ employees
Biotechnology
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About Senior Scientist/Principal Scientist, Encoded Peptide Libraries

  About the Role

  5000+! That's the number of associates in Biomedical Research at Novartis. This division is the innovation engine of Novartis, focusing on powerful new approaches that will help produce therapeutic breakthroughs for patients. The Discovery Sciences department (DSc) at NIBR drives drug discovery and champions innovative approaches such as Radioligand Therapeutics (RLT).

  The Chemical Genetics group in DSc, Basel/Switzerland, is seeking a highly motivated, curious, and innovative scientist who is interested in making an impact on drug discovery through scientific technologies and by boosting our endeavors in the identification, characterization, and development of novel RTLs and emerging therapeutic modalities. We are a highly collaborative, global group of researchers exploring the interface of chemistry and biology for projects in early drug discovery. More specifically, we apply and develop encoded library technologies for the discovery of low molecular weight and peptide binders to disease relevant targets and explore emerging drug modalities as novel innovative path to therapeutics. Our group is part of the larger DSc department that encompasses a spectrum of sophisticated capabilities for successful, state-of-the-art drug discovery.

  Location: Basel, Switzerland #LI-Hybrid

  Your responsibilities:

  Your responsibilities include, but are not limited to:

  • Design, execute, and analyze encoded peptide library screening campaigns for drug discovery projects with an emphasis on Radioligand therapy (RLT) projects

  • Innovate and further develop existing encoded library technologies and explore novel screening approaches

  • Contribute experimentally and intellectually to early drug discovery projects and the exploration of novel drug modalities by working in multidisciplinary and collaborative global teams

  • Prepare and communicate results at internal and external meetings, and in scientific publications.

  • Mentor and develop junior colleagues in the laboratory.

  Diversity & Inclusion / EEO

  We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

  Role Requirements

  • The candidate holds a PhD, or alternatively an MSc with 5+ years of experience in industry, with a background in one or more of the following areas: chemical biology, biochemistry/biophysics, molecular biology, synthetic biology, assay development.

  • Strong interest in exploring novel screening technologies and therapeutic approaches for drug discovery.

  • Curiosity, scientific agility, and interdisciplinary mindset (chemistry, biology, technology).

  • Interest in working in matrixed and collaborative teams. Excellent interpersonal skills.

  • Ability to adapt to scientific challenges and to generate innovative ideas/solutions.

  • Excellent communication and presentation skills in oral and written English.

  Desirable Requirements:

  • Practical knowledge with encoded library screening: e.g. mRNA- or phage-display, DNA-encoded libraries

  • Expertise in identifying and characterizing LMW ligands and exploring novel screening technologies at the interface of chemistry and biology

  • Experience with identifying and developing ligands in the context of RLTs and vectorized therapeutics

  • Experience with developing and applying tools for analyzing large, complex data sets

  Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here:

  https://www.novartis.com/about/strategy/people-and-culture

  You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards

  Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to

  [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

  Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

  Division

  Biomedical Research

  Business Unit

  DSc

  Location

  Switzerland

  Site

  Basel

  Company / Legal Entity

  Novartis Pharma AG

  Functional Area

  Research & Development

  Job Type

  Full Time

  Employment Type

  Regular

  Shift Work

  No

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