Job Description

　　Are you passionate about revolutionizing drug delivery and shaping the future of pharmaceutical sciences? Join our dynamic and multidisciplinary research group that is at the forefront of drug discovery and development.

　　Our company's Research Laboratories Boston, is focused on driving discovery research. Our multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with our company's world-class R&D expertise in small molecules, peptides, biologics and nucleic acids. Located within the heart of the Massachusetts biomedical community, research conducted in our laboratories spans exploratory biology through early clinical development and is an integral part of our company's powerful world-class network of drug and vaccine discovery.

　　Discovery Pharmaceutical Sciences (DPS) is a multi-disciplinary research group that enables drug discovery and drug product development through application of pharmaceutical science and drug delivery research from target identification through clinical candidate selection for both small and large molecules. DPS influences molecular design of novel therapeutics through physicochemical property profiling, de-risking strategies, and communication across functions and downstream to development partners. We further utilize our expertise to develop and study prototype formulations intended for clinical use, and deliver robust Good Laboratory Practice formulations. In aggregate, our team enables the transition of the right molecules from discovery to clinical formulation development with clinical formulation strategies in place. This position offers the unique opportunity to contribute to the development of innovative drug delivery technologies and the advancement of novel drug products through solving unique challenges in delivering diverse modalities and driving scientific rigor to maintain the leading position of DPS in pharmaceutics assessment.

　　Job Responsibilities:

　　DPS in Boston, MA is seeking a Principal Scientist to join our department. The candidate should have a creative passion for identifying and applying effective drug delivery technologies and pharmaceutics methods as well as a track record of driving results and rapidly progressing from idea conception to in-vitro & in-vivo evaluation. The Principal Scientist will:

　　Identify and champion impactful pipeline-driven innovations to solve unique Discovery program challenges of delivery of diverse modalities including small molecules, peptides and biologics.

　　Challenge the scientific direction within the space and inspire scientific rigor to bring novel and innovative tools to aide in keeping DPS at the front of pharmaceutics assessment in discovery.

　　Help develop necessary subject matter experts within the group through mentorship and coaching to identify and progress optimal drug candidates of all modalities.

　　Actively explore external (commercial and academic) opportunities to engage new technologies related to drug delivery, pharmaceutics, and other areas relevant to our company's drug discovery/development programs

　　Education minimum requirements:

　　Ph.D. with eight (8) years of experience or M.S. with ten (10) years of experience in pharmaceutical sciences, chemistry, chemical / biochemical engineering or related disciplines and relevant experienceRequired Experience and Skills:

　　Experience in driving innovative research in oral and injectable drug delivery of small molecules and/ peptides.

　　Strong leadership/interpersonal skills and motivation to work in a team environment with cross-functional interactions.

　　Enterprise mindset with decision making driven by an appropriately balanced consideration of driving the business and developing staff.

　　Demonstrated experience solving program challenges by leveraging strong scientific fundamentals in related subject areas including organic chemistry, analytical chemistry, physical chemistry, biopharmaceutics, process development, or engineering.

　　Familiarity with early development and commercialization challenges through drug product development experience

　　Preferred Experience and Skills:

　　Experience in pre-clinical / clinical formulation development and physico-chemical characterization.

　　Advanced computation, data analysis, and visualization skills

　　Strong record of patent applications / patents

　　Strong record of external peer-reviewed publications

　　Demonstration of external scientific presence and influence

　　NOTICE FOR INTERNAL APPLICANTS

　　In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

　　If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

　　#EligibleforERP

　　Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

　　Current Employees apply HERE (https://wd5.myworkday.com/msd/d/inst/1422$1533/rel-task/3001$14.htmld)

　　Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)

　　US and Puerto Rico Residents Only:

　　Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.

　　We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

　　EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088_EEOC_KnowYourRights_10_20.pdf)

　　EEOC GINA Supplement​

　　Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp_%20English_formattedESQA508c.pdf)

　　We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

　　Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)

　　U.S. Hybrid Work Model

　　Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

　　Search Firm Representatives Please Read Carefully

　　Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

　　Employee Status:

　　Regular

　　Relocation:

　　Domestic

　　VISA Sponsorship:

　　Yes

　　Travel Requirements:

　　10%

　　Flexible Work Arrangements:

　　On-Site

　　Shift:

　　1st - Day

　　Valid Driving License:

　　No

　　Hazardous Material(s):

　　N/A

　　Requisition ID: R277047