Senior Laboratory Science Professional - 32435 University Staff

　　Description

　　University of Colorado Anschutz Medical Campus

　　School of Medicine | Department of Medicine | Division of Pulmonary Sciences and Critical Care

　　Job Title: Senior Laboratory Science Professional

　　Position: #00818555 – Requisition: #32435

　　Job Summary:

　　The research in the Schwartz/Yang Lab focuses on understanding how a combination of genetic factors and environmental exposures contribute to an individual's disposition to develop lung disease. We conduct cutting-edge basic and translational research in pulmonary fibrosis and sarcoidosis, focusing on genetics, genomics, epigenetics, animal models, and molecular determinants of human disease. In the laboratory, we use genome editing approaches to manipulate genetic variants and expression of key genes in primary cell and animal models. Computational approaches include genetic screens for genes that interact with MUC5B, identification of biomarkers of early disease, and single cell and spatial transcriptomic technologies. Our ultimate goal is to understand the early mechanisms of lung fibrosis, develop biomarkers for early detection, and ultimately identify therapeutics for early treatment of disease.

　　Our pulmonary fibrosis genetics and genomics research seeks to uncover the genetic and environmental determinants of pulmonary fibrosis. Our ultimate goal is to use genetic variants, alone or in combination with gene expression fingerprints and/or peripheral blood biomarkers, to treat patients based on the genetic subtype of IPF they have, and to initiate treatment in the preclinical stages of disease rather than at a late stage when lung is scarred irreversibly, and prognosis is poor.

　　We are focusing on diseases with the usual interstitial pneumonia (UIP) radiologic and pathologic pattern, specifically, idiopathic pulmonary fibrosis (IPF), chronic hypersensitivity pneumonitis (CHP), and rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Our group identified a gain-of-function genetic variant in the airway mucin MUC5B as the key predisposition factor for development of early and established forms of IPF, CHP, and RA-ILD. We are using cutting edge technologies of spatial and single cell profiling as well as multi-omic integration methods to pursue novel biology, treatment, and biomarkers. For this work, we collect and process human blood, tissue, and other biospecimen.

　　This individual will be responsible for receiving and processing human biospecimens and associated data. They will also perform basic experiments such as genotyping and quantitative PCR assays. This position requires basic laboratory experience, detailed record keeping, attention to detail, and the ability to work with windows-based software and database interfaces. This individual must work well independently and as a part of the larger team.

　　Key Responsibilities:

　　Barcoding, tracking and organization of samples and data received in the laboratory, including tasks such as uploading CT scan into our study database, tracking of biospecimens and isolated nucleic acids in freezers and LIMS.

　　Processing of human blood and isolation of peripheral blood mononuclear cells.

　　Nucleic acid (DNA and RNA) isolation from blood and lung tissue and quality control of isolated nucleic acids.

　　Genotyping and RNA analysis including Taqman, RT-qPCR, targeted DNA and RNA sequencing on MiSeq.

　　Work Location:

　　Onsite – this role is expected to work onsite and is located on the Anschutz Medical Campus in Aurora, Colorado. Must be willing and able to occasionally work on weekends and outside of regular business hours when required.

　　Why Join Us:

　　About the Division of Pulmonary Sciences and Critical Care Medicine

　　Thank you for your interest in the Division of Pulmonary Sciences and Critical Care Medicine at the University of Colorado! Our over 140 faculty are located across four sites: the University of Colorado Anschutz Medical Campus, National Jewish Health, Denver Health, and the VA Eastern Colorado Health Care System.

　　We are very proud of our long and illustrious history. Many seminal discoveries in pulmonary and critical care medicine occurred here in Denver, including advances in tuberculosis, interstitial lung disease, airway disease, cancer, and critical care. Many of our former trainees have taken leadership roles in academic medicine, including Division and Department Chairs, Deans, and American Thoracic Society Presidents.

　　However, we do not rest on our laurels! We continue to enhance all aspects of our division and training program, and as a result, we have seen tremendous and sustained growth. The clinical practice sites have built new hospitals, and there are multiple new research buildings across the campuses. We have been fortunate to recruit tremendous new faculty members while retaining many of our former trainees.

　　About the University of Colorado Anschutz Medical Campus

　　The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education, and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals - UCHealth University of Colorado Hospital (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.uchealth.org/locations/uchealth-university-of-colorado-hospital-uch/) and Children's Hospital Colorado (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.childrenscolorado.org/locations/anschutz-medical-campus-aurora/) - that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $650 million in research grants. For more information, visit www.cuanschutz.edu (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.cuanschutz.edu/) .

　　Why work for the University?

　　We have AMAZING Benefits and offer exceptional amounts of holiday, vacation, and sick leave!

　　The University of Colorado offers an excellent benefits package including:

　　Medical: Multiple plan options

　　Dental: Multiple plan options

　　Additional Insurance: Disability, Life, Vision

　　Retirement 401(a) Plan: Employer contributes 10% of your gross pay

　　Paid Time Off: Accruals over the year

　　Vacation Days: 22 (maximum accrual 352 hours)

　　Sick Days: 15 (unlimited maximum accrual)

　　Holiday Days: 10

　　Tuition Benefit: Employees have access to this the benefit on all CU campuses

　　ECO Pass: RTD Bus and light rail service

　　Additional Perks & Programs: Click here to access a few more Perks and Programs (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.cu.edu/cu-careers/perks/cu-system)

　　To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.cu.edu/employee-services/benefits-wellness) .

　　Diversity and Equity:

　　The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty, and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

　　Qualifications:

　　Minimum Qualifications

　　Bachelor's degree in biology, molecular biology, chemistry, genetics, or related field.

　　A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis.

　　Two (2) years of professional level research experience.

　　Applicants must meet minimum qualifications at the time of hire.

　　Preferred Qualifications

　　Master's degree in biology, molecular biology, chemistry, genetics, or related field.

　　Three (3) years of experience in an experimental or wet laboratory.

　　One (1) year of research animal experience.

　　Experience working with human or animal cell cultures in a research environment.

　　Knowledge, Skills, and Abilities

　　Advanced knowledge of basic laboratory techniques including safety procedures and techniques.

　　Ability to communicate effectively, both in writing and orally.

　　Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.

　　Outstanding customer service skills.

　　Demonstrated commitment and leadership ability to advance diversity and inclusion.

　　Knowledge of basic human anatomy, physiology, medical terminology.

　　Ability to interpret and master complex research protocol information.

　　How to Apply:

　　For full consideration, please submit the following document(s):

　　A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position.

　　Curriculum vitae / Resume

　　Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address.

　　Questions should be directed to: Ivana Yang, [email protected] (https://apptrkr.com/get_redirect.php?id=4956536&[email protected])

　　Screening of Applications Begins:

　　Screening of applications begins on January 28 th , 2024.

　　Anticipated Pay Range:

　　The starting salary range ( or hiring range ) for this position has been established as $49,515 - $62,983.

　　The above salary range ( or hiring range ) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

　　Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

　　Total Compensation Calculator: http://www.cu.edu/node/153125 (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=http://www.cu.edu/node/153125)

　　ADA Statement:

　　The University will provide reasonable accommodation to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at [email protected] (https://apptrkr.com/get_redirect.php?id=4956536&[email protected]) ​.

　　Background Check Statement:

　　The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

　　Vaccination Statement:

　　CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://www.cdc.gov/vaccines/schedules/downloads/adult/adult-combined-schedule.pdf) . If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program (https://apptrkr.com/get_redirect.php?id=4956536&targetURL=https://research.cuanschutz.edu/ehs/home/divisions/occupational-health/oh-enrollment) .

　　Application Materials Required: Cover Letter, Resume/CV, List of References

　　Job Category : Research Services

　　Primary Location : Aurora Department: U0001 -- Anschutz Med Campus or Denver - 20219 - SOM-MED-PUL GENERAL OPERATIONS

　　Schedule : Full-time

　　Posting Date : Jan 23, 2024

　　Unposting Date : Ongoing Posting Contact Name: Ivana Yang Posting Contact Email: [email protected] (https://apptrkr.com/get_redirect.php?id=4956536&[email protected]) Position Number: 00818555

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　　The University of Colorado does not discriminate on the basis of race, color, national origin, sex, age, pregnancy, disability, creed, religion, sexual orientation, gender identity, gender expression, veteran status, political affiliation, or political philosophy. All qualified individuals are encouraged to apply.